The Master of Patient Safety and Healthcare Quality (MPSHQ) at Duke-NUS Medical School, jointly conferred with the National University of Singapore, is Southeast Asia's pioneering master's program dedicated to advancing robust healthcare systems that ensure consistent quality and safety. The curriculum integrates principles of systems engineering, human factors, and clinical epidemiology to reduce medical errors and drive institutional accountability and systemic redesign. The inaugural cohort graduated in 2025, indicating the program's current and active status in shaping multidisciplinary healthcare leaders.